Integrin beta 2 antibody (PE-Cy5)

Catalog No. ABIN7673797

This anti-Integrin beta 2 antibody is a Mouse Monoclonal antibody detecting Integrin beta 2 in FACS. Suitable for Human.

Quick Overview for Integrin beta 2 antibody (PE-Cy5) (ABIN7673797)

Target: Integrin beta 2 (ITGB2)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Integrin beta 2 antibody is conjugated to PE-Cy5

Application: Flow Cytometry (FACS)

Clone: TS1-18-1-2-11

Product Details anti-Integrin beta 2 Antibody (PE-Cy5)

Purpose: PE-Cy5 Anti-Human CD18 Antibody

Purification: 0

Purity: 0

Isotype: IgG1, kappa

Application Details

Application Notes: Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0. 1 % sodium azide, 1 % BSA, pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: 4 °C

Storage Comment: 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for Integrin beta 2

Target: Integrin beta 2 (ITGB2)

Alternative Name: CD18

Background:

Synonyms: CD18|Cell surface adhesion glycoproteins LFA-1/CR3/p150+95 subunit beta|Complement receptor C3 subunit beta|Integrin beta-2|Itgb2

Background: CD18 is a 90-95 kD type I transmembrane protein also known as integrin β2 subunit, LFA-1 β subunit, and β2 integrin. CD18 non-covalently associates with CD11a, CD11b or CD11c. CD18 is expressed on all leukocytes. CD18 and associated α chains function in adhesion and signaling in hematopoietic cells.

Molecular Weight: 0

Gene ID: 3689

UniProt: P05107

Pathways: NF-kappaB Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation